Wegener′s granulomatosis disease mimicking pulmonary tuberculosis

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Neutrophil chemotaxis in Wegeners granulomatosis and idiopathic pulmonary fibrosis

Background: The presence of anti-neutrophil cytoplasmic antibodies (ANCA) in Wegener’s granulomatosis (WG), implicate the neutrophil as a key effector cell. Previous studies have reported elevated neutrophil counts in the lung although the determinants of neutrophil chemotaxis in the WG lung are unknown. Methods: BALF cell counts, myeloperoxidase (MPO) and chemokines were measured in 27 patient...

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ژورنال

عنوان ژورنال: The Journal of Association of Chest Physicians

سال: 2015

ISSN: 2320-8775

DOI: 10.4103/2320-8775.158863